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上海欣諭儀器有限公司>技術(shù)文章>生產(chǎn)型藥機(jī)的冷井要求以及怎么實(shí)現(xiàn)前后倉無菌隔離的

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生產(chǎn)型藥機(jī)的冷井要求以及怎么實(shí)現(xiàn)前后倉無菌隔離的

閱讀:123          發(fā)布時間:2024-9-3

XY-SGY系列凍干機(jī) 冷阱與箱體都是分隔的,通過一個氣流通道連接。  采用整合的水平冷阱。更大規(guī)格的設(shè)備冷阱安裝在箱體后面。

本項(xiàng)目冷阱排布形式請參閱附件的圖。

The cold trap of XY-SGY series freeze-drying machine is separated from the box and is connected by an air flow channel. Equipment below uses an integrated horizontal cold trap. The larger equipment cold trap is installed behind the box.


 設(shè)備容器材料為AISI 316L 不銹鋼。冷阱容器內(nèi)部機(jī)械拋光至<0.75μmra>

接管有一定的傾斜度,以確保液體的排出,長徑比小于6:1。

冷阱保溫采用聚合發(fā)泡材料或聚合發(fā)泡材料與玻璃纖維的混合材料,外覆金屬板裝飾。

冷阱側(cè)面安裝一個帶照明的直徑150mm (6") 觀察鏡。

冷阱都裝有一個位于低點(diǎn)的排放口。所有的排放管都焊接保護(hù)網(wǎng),以防止冰塊堵塞。

在冷阱的頂部安裝有一個噴嘴,用于噴灑熱水或蒸汽,在工藝處理的Z后階段進(jìn)行化霜。

The vessel is fabricated from AISI 316L stainless steel. The internal surfaces of the condenser vessel are mechanically polished to <>

Nozzles are pitched to ensure drainage of liquids and have an aspect ratio less than 6:1 to ensure sterilisation should this option be included.

The condenser vessel is externally insulated with a polymer foam insulation and clad with sheet metal to protect the insulation material.

An illuminated 150mm (6") sight glass is fitted to the side of the condenser body. 

A low point drain is fitted in the condenser. The drain is fitted with a welded mesh cover to prevent ice blocking the drain. 

A spray ball(s) is fitted in the roof of the condenser to spray hot water for removal of ice at the end of the process.

The condensing surface within the condenser body comprises a number of polished 316L stainless steel tubes welded to form a series of coils, configured to allow oil drainage. The coils have an external finish of <0.75mra. a="" series="" of="" coils="" are="" manifolded="" in="" parallel="" to="" form="" a="" coil="" circuit.="" each="" circuit="" is="" cooled="" by="" the="" direct="" expansion="" of="" refrigerant="" gas="" supplied="" by="" a="" dedicated="" compressor.="" the="" number="" of="" circuits="" and="" compressors="" varies="" between="" lyomax="" models,="" however="" the="" condensing="" surface="" area="" of="" all="" models="" is="" at="" least="" equivalent="" to="" the="" shelf="" surface="" area="" to="" provide="" optimum="" condenser="" performance="" during="" peak="">


在冷阱內(nèi)的冷凝面包括幾組拋光的不銹鋼管焊接成連續(xù)的螺旋狀

盤管。冷凝管的外表面拋光<0.75μmra>

機(jī)直接供應(yīng)的制冷氣體直接膨脹制冷。冷凝管和壓縮機(jī)的數(shù)量取

決于冷凝器的大小。冷凝面積與板層面積的比例基本上1:1,這樣

可以在升華的峰值時得到Z佳的冷阱捕冰效果。

冷阱Z低溫度可達(dá)到 -75°C,空載降溫速度是在30 分鐘內(nèi)從 +20°C 到 -40°C。

The minimum condenser temperature is -75°C and cooldown from +20°C to -40°C is achieved within 30 minutes, under no load conditions.


每組冷凝盤管都通過RTD 溫度探頭監(jiān)控,溫度探頭安裝在冷凝管的中間部位,可以在不進(jìn)入冷阱的情況下更換溫度探頭。

Each condenser cooling circuit is monitored by an RTD temperature probe which is mounted in a thermal well located approximately mid-length along one coil of each circuit to enable its removal for calibration and service without the need to open the condenser

冷井.jpg

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